Viagra Professional (Sildenafil): Revealing The Truth

For more than twenty years Viagra has been a unique phenomenon of the global pharmaceutical market. The manufacturer has convinced us all that Sildenafil Citrate can put new life into the weakest erection so that millions of men were happily queuing ready to spend the last dollar on these magical blue pills sold at a scandalously high price.

Viagra Professional (Sildenafil): Revealing The TruthViagra proved to be a miracle with its 95% effectiveness, exceptional safety, and few contraindications. But there was one catch: the world was starving of CHEAP ED medications. The deficit of reliable and affordable erectile remedies inspired pharmacists to develop Sildenafil-based Viagra generics that would be identical to the original preparation in respect of therapeutic action, strength, and quality with small variations in a size, forms, composition, and time of absorption (read more information about bioequivalence of generic drugs at My Canadian Pharmacy).

Despite the evident benefits of generic Viagra, impotent patients are very skeptic about their effectiveness thinking there is always something wrong with drug alternatives. On the Internet, generic products like Viagra Professional are the subject of much controversy. And Canadian Pharmacy Online is here to shed light on the most popular questions about generic Viagra.

Are generics safe?

FDA, the world’s leading drug control authority, regard generic drugs as essential medical options allowing people to have a greater access to cost-friendly health care. Generics are the copies of branded medications as they contain the same active substances as the original medication. Before mass-production, generic manufacturers have to prove their products passed the same rigid standards of quality, performance, and efficacy as the innovator medication.

Organizations like FDA regularly conduct clinical trials to compare generic products to their brand counterparts, monitor generic-related adverse events, and publish the obtained results in the open sources. Hence, you can rest assured – Viagra Professional meets the same specifications and requirements as its original.

Can generic Viagra Professional be used in specific populations?

Patients looking for Viagra Professional at My Canadian Pharmacy often ask us this question. Premarketing clinical studies of Sildenafil (the main agent of Viagra and its bioequivalent generics) confirmed that there are no significant differences in response to Sildenafil between young and senior (over 65) users. Actually, the dose adjustment is required for those individuals with the history of severe renal, hepatic, retinal, or cardiac disorders. Notably that mild to moderate conditions of liver, kidneys or heart do not require the specific selection of Viagra Professional dose.

What effect does Viagra Professional have on blood?

 Viagra Professional is vasodilator – it makes blood vessels expand what results in the mild drop of blood pressure. Patients suffering from hypotension or any other cardiovascular conditions (irregular heart rhythm, unstable angina, cardiac insufficiency, etc.) and taking antihypertensive drugs or cardiac medications need close medical care and the dose adjustment if they decide to start Sildenafil therapy.

How does Viagra Professional interact with other drugs?

With the majority of medicaments, Viagra Professional does not interact at all or just has minor drug-to-drug interactions. However, severe interactions are possible if a patient combines Sildenafil Citrate (active agent of generic Viagra) with the next pharmaceuticals:

  • Any organic nitrates,
  • CYP3A inhibitors,
  • Oral antifungal remedies,
  • Antibiotics,
  • Alpha blockers,
  • Antihypertensive agents,
  • HIV protease inhibitors,
  • Other PDE5 inhibitors.

Can generic Viagra cause prolonged erection?

If a man has anatomic features of the phallus (deformation, penile surgery, shaft damage, angulation of ureter) pre-existing blood cell conditions like leukemia, hemophilia or anemia, he might experience acute priapism (an unusually long and embarrassing erection often accompanied by pain in penile tissues) for about 5 hours after taking a Viagra Professional pill. Individuals without these health problems are not prone to develop prolonged erection. An excessive dose of Sildenafil may provoke priapism as well. To avoid abuse and severe morbidity, a patient is advised to completely follow the product instruction.

Does Viagra Professional induce vision impairment?

Men treating their erectile disorder with generic Viagra sometimes complain of permanent blurred vision. According to the post-marketing research of Sildenafil Citrate, patients with pre-existing ocular diseases or retinal anatomical defects are at risk of developing visual disorder while being on Viagra Professional. The incidents of color discrimination and vision disturbance are explained by the fact that Sildenafil in a less degree also inhibits phosphodiesterase-6 (an enzyme produced in the retina).

Is Viagra Professional addictive?

The composition of Viagra Professional includes Sildenafil citrate and auxiliary natural ingredients aimed to enhance the action of the main substance. There are no synthetic chemicals in generic Viagra that can induce physical dependence in men (remember, regulatory agencies are continuously monitoring and reporting on generics and what they do in the body). Nevertheless, Viagra Professional may develop psychological dependence in males who take it for the recreational use or administer it with illicit drugs (so-called poppers or club pills).

Can generic Viagra Professional increase libido?

It is a typical question asked by those people who are not familiar with Sildenafil’s mechanism of action. The answer is no. Viagra Professional starts working once a male’s organism activates the production of cGMP (cyclic guanosine monophosphate) in the penis. This activation results in blood vessels vasodilation (widening) and, hence, enhanced blood flow to the penile shaft.

Phosphodiesterase type 5 (PDE5) prevents the formation of cGMP to keep the normal chemical balance in the body. Sildenafil binds to the molecules of PDE5 and breaks them. The matter is that the production of cGMP is only possible under sexual excitement. Consequently, generic Viagra helps a man improve his erection but it does not boost his sexual appetite.

Aging and Disability Affect Misdiagnosis of COPD and Treatment With Viagra

Study objectives: This study investigated to what extent a diagnosis of COPD is erroneously made or the disease remains unrecognized in elderly asthmatic patients, and identified factors leading to misdiagnosis and underdiagnosis of asthma in such patients.

Design: A multicenter study involving 24 Italian pulmonary or geriatric institutions.

Patients: One hundred twenty-eight asthmatic patients (98 women, 76.6%) aged 73 ± 6.4 years (mean ± SD) were selected from the cohort of the Salute Respiratoria nell’Anziano (respiratory health in the elderly) study.

Methods: All patients underwent a clinical evaluation that included clinical history and spirometry with a bronchodilator test. A diagnosis of asthma was based on criteria proposed by international guidelines adapted to the elderly population. A multidimensional geriatric assessment was performed to estimate physical and cognitive impairments and mood state. Finally, the diagnosis of respiratory disease previously made by a doctor, if any, was recorded.

Results: Of asthmatic patients, COPD had been improperly diagnosed in 19.5%, whereas 27.3% of asthmatic patients did not report any previous diagnosis of asthma. The main correlates of misdiagnosis were older age and disability. Conversely, underdiagnosis was associated with better functional conditions, expressed by spirometry, even when wheezing or a significant response to the bronchodilator test occurred.

Conclusions: Asthma in the elderly is frequently confused with COPD. Misdiagnosis can be related to older age and to greater degree of disability. Asthma in patients with mild functional impairment may be underdiagnosed in spite of overt respiratory symptoms suggestive of asthma.

Abbreviations: FEV1% = FEV1 percentage of predicted; GDS = geriatric depression scale; MMSE = Mini Mental State Examination; SARA = Salute Respiratoria nell’Anziano; 6MWT = 6-min walking test

For many years, asthma has been considered a disease of childhood or young adulthood, although it is not uncommon in the elderly.1 Elderly asthmatic patients mainly include subjects who acquired the disease during childhood or adolescence and whose disease progressed over time or relapsed after periods of remission; however, the first manifestations of asthma may also occur in the late adulthood or after 65 years of age. The reasons why asthma is rarely diagnosed in the elderly are unclear. The presumed low prevalence of asthma in the elderly can be attributed to greater difficulties encountered when providing a correct diagnosis of asthma in the elderly as opposed to the younger population. It is likely that factors pertaining to aging play a significant role.